Article details

Journal
Biotechnology and Food Science
Volume 82 Number 2
Year
2018
Title
In vitro study of hesperetin Schiff bases antioxidant activity on rat liver mitochondria
Authors

Anna Sykuła 1* , Vitali T. Cheshchevik 2 , Nina G. Cheshchevik 2 , Aliaksandr Dzeikala 1 , Elżbieta Łodyga-Chruścińska 1 cheap nfl jerseys from china
1Institute of General Food Chemistry, Faculty of Biotechnology and Food Chemistry, Lodz University of Technology, Stefanowskiego Street 4/10, 90-924 Lodz, Poland
2Department of Biotechnology, Polessky State University, Dneprovskoy Flotilii Street 23, 225710 Pinsk, Belarus
*anna.sykula@p.lodz.pl

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Pages: 151-159
Abstract

Three hesperetin Schiff bases: hesperetin thiosemicarbazone (HTSC), hesperetin isoniazone (HIN) and hesperetin benzhydrazone (HHSB) have been synthesized and characterized by using analytical and spectral techniques. The influence of substituents on hesperetin antioxidant activity has been studied in vitro using mitochondrial assays. The studied compounds have been found to exhibit both antioxidant and pro-oxidant activity.

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Keywords
hesperetin, Schiff bases, isolated mitochondria, antioxidant activity, pro-oxidant activity
 
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