Article details

Journal
Zeszyty naukowe PŁ, Chemia Spożywcza i Biotechnologia
Zeszyt 71
Year
2007
Title
The study of the interactions between ketoprofen and N-acetyl-L-tyrosine ethyl ester
Authors

Krzysztof Zgolak, Anna Jeszka, Tomasz Kabziński
Institute of General Food Chemistry,
Faculty of Biotechnology and Food Sciences,
Technical University of Lodz

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Pages: 49 - 58
Abstract

Investigation of interactions between ketoprofen and N-acetyl-L-tyrosine ethyl ester are reported. Formation of the complex was studied using fluorescence spectroscopy and computer modeling. The fluorescence decay time let us determine the quenching mechanism and thus conclude that the complex is formed in the ground-state. The complex structure was than optimised using the computer programme proving the formation of two unequal hydrogen bonds between ketoprofen and tyrosine molecules.

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